Administering
PrSILEO®
(Dexmedetomidine hydrochloride
oromucosal gel)
Watch the video below to see how to administer SILEO.
OPENING OF THE CHILD-RESISTANT CARTON
Push to break the seals.
Push the button and pull to open.
Make sure that the package is closed correctly so that it remains child-resistant. When closing, the SILEO logo must be on the same side on both the inner and the outer carton so that the button becomes visible.
PREPARATIONS FOR DOSING
WEAR GLOVES
Wear impermeable disposable gloves when handling SILEO and handling the oral syringe.
HOLD PLUNGER
Hold the oral syringe from the plunger so that you can see the dot markings.
SYRINGE SET-UP
ROTATE RING
When using the syringe for the first time, rotate the dosing ring towards the barrel until it reaches the opposite end of the plunger.
Continue rotating the ring until it reaches the opposite end of the plunger.
Stop rotating once you have reached the barrel.
DOSE SELECTION
SET THE DOSE
Rotate the dosing ring towards the end of the plunger, and position it so that the side nearest the barrel is in line with the graduation mark (black line) and the prescribed number of dots are shown between the barrel and the dosing ring.
Do not pull the plunger!
CONFIRM THE DOSE
Make sure that you count the dots from the correct part of the plunger (shown in yellow) and that the ring is in line with the graduation mark (shown with the yellow arrow).
PULL CAP (TIGHT)
Pull the cap strongly while holding the barrel. Note: The cap is very tight (pull, do not twist). Save the cap for replacement.
DOSING
DOSE INTO CHEEK
Place the oral syringe tip between your dog’s cheek and gum, and press the plunger until the dosing ring causes the plunger to stop.
IMPORTANT: The gel should not be swallowed. If the gel is swallowed, it may not be effective.
Avoid feeding and giving treats for 15 minutes after giving SILEO.
BACK TO PACKAGE
Recap the oral syringe and return it to the outer package as SILEO is sensitive to light. Make sure that the carton is closed properly. Keep the product out of sight and reach of children at all times. Remove and discard gloves. Use or discard syringe contents within 4 weeks after opening the syringe.
ADMINISTERING FOLLOWING DOSES
When the same syringe is used for redosing, repeat the previous “Set the dose” and “Confirm the dose” parts of the instructions.
